{"id":27,"date":"2017-10-22T17:02:55","date_gmt":"2017-10-22T15:02:55","guid":{"rendered":"http:\/\/www.stichtingcranias.nl\/?page_id=27"},"modified":"2024-09-16T09:07:40","modified_gmt":"2024-09-16T07:07:40","slug":"onderzoek","status":"publish","type":"page","link":"https:\/\/www.stichtingcranias.nl\/index.php\/onderzoek\/","title":{"rendered":"Onderzoek"},"content":{"rendered":"\n

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PROTOCOL TE STARTEN ONDERZOEK<\/strong><\/p>\n

Onderzoeksprotocol PAC-ELR studie (2024)<\/p>\n

download=“filename”<\/a><\/p>\n

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AFGEROND ONDERZOEK<\/strong><\/p>\n

Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial. March 2023. The Lancet 401 (10385). DOI: 10.1016\/S0140-6736(23)00575-5. \u00a0<\/em><\/p>\n

Susanne G H Olthuis, F Anne V Pirson, Florentina M E Pinckaers, Wouter H Hinsenveld, Daan Nieboer, Angelique Ceulemans, Robrecht R M M Knapen, M M Quirien Robbe, Olvert A Berkhemer, Marianne A A van Walderveen, Geert J Lycklama \u00c0 Nijeholt, Maarten Uyttenboogaart, Wouter J Schonewille, P Matthijs van der Sluijs, Lennard Wolff, Henk van Voorst, Alida A Postma, Stefan D Roosendaal, Anouk van der Hoorn, Bart J Emmer, Menno G M Krietemeijer, Pieter-Jan van Doormaal, Bob Roozenbeek, Robert-Jan B Goldhoorn, Julie Staals, Inger R de Ridder, Christiaan van der Leij, Jonathan M Coutinho, H Bart van der Worp, Rob T H Lo, Reinoud P H Bokkers, Ewoud I van Dijk, Hieronymus D Boogaarts, Marieke J H Wermer, Adriaan C G M van Es, Julia H van Tuijl, Hans G J Kortman, Rob A R Gons, Lonneke S F Yo, Jan-Albert Vos, Karlijn F de Laat, Lukas C van Dijk, Ido R van den Wijngaard, Jeannette Hofmeijer, Jasper M Martens, Paul J A M Brouwers, Tomas Bulut, Michel J M Remmers, Thijs E A M de Jong, Heleen M den Hertog, Boudewijn A A M van Hasselt, Anouk D Rozeman<\/strong>, Otto E H Elgersma, Bas van der Veen, Davy R Sudiono, Hester F Lingsma, Yvo B W E M Roos, Charles B L M Majoie, Aad van der Lugt, Diederik W J Dippel, Wim H van Zwam, Robert J van Oostenbrugge; MR CLEAN-LATE investigators.<\/p>\n

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The frequency of CYP2C19 loss-of-function variants in patients with non-cardioembolic ischemic stroke or transient ischemic attack in the Dutch population.\u00a0<\/em>Lotte van den Heuvel, Henricus J Vermeer, Henk Kerkhoff<\/strong>, Bob Roozenbeek, Elles Zock<\/strong>. 2022 accepted for publication.<\/p>\n

Safety and\u00a0efficacy of aspirin, unfractionated heparin, both, or neither during<\/em> endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre,<\/em> randomised controlled trial<\/em>. Lancet. 2022 Mar 12;399(10329):1059-1069. doi: 10.1016\/S0140-6736(22)00014-9. Epub 2022 Feb 28. PMID: 35240044.
van der Steen W, van de Graaf RA, Chalos V, Lingsma HF, van Doormaal PJ,Coutinho JM, Emmer BJ, de Ridder I, van Zwam W, van der Worp HB, van der Schaaf\u00a0I, Gons RAR, Yo LSF, Boiten J, van den Wijngaard I, Hofmeijer J, Martens J,\u00a0Schonewille W, Vos JA, Tuladhar AM, de Laat KF, van Hasselt B, Remmers M, Vos D,\u00a0Rozeman A<\/strong>, Elgersma O, Uyttenboogaart M, Bokkers RPH, van Tuijl J, Boukrab I,\u00a0van den Berg R, Beenen LFM, Roosendaal SD, Postma AA, Krietemeijer M, Lycklama\u00a0G, Meijer FJA, Hammer S, van der Hoorn A, Yoo AJ, Gerrits D, Truijman MTB,\u00a0Zinkstok S, Koudstaal PJ, Manschot S, Kerkhoff H<\/strong>, Nieboer D, Berkhemer O, Wolff\u00a0L, van der Sluijs PM, van Voorst H, Tolhuisen M, Roos YBWEM, Majoie CBLM, Staals\u00a0J, van Oostenbrugge RJ, Jenniskens SFM, van Dijk LC, den Hertog HM, van Es ACGM,\u00a0van der Lugt A, Dippel DWJ, Roozenbeek B; MR CLEAN-MED investigators.<\/p>\n

A Randomized Trial of\u00a0Intravenous Alteplase before Endovascular Treatment for Stroke.<\/em> N Engl J Med.\u00a02021 Nov 11;385(20):1833-1844. doi: 10.1056\/NEJMoa2107727. PMID: 34758251
LeCouffe NE, Kappelhof M, Treurniet KM, Rinkel LA, Bruggeman AE, Berkhemer\u00a0OA, Wolff L, van Voorst H, Tolhuisen ML, Dippel DWJ, van der Lugt A, van Es\u00a0ACGM, Boiten J, Lycklama \u00c0 Nijeholt GJ, Keizer K, Gons RAR, Yo LSF, van\u00a0Oostenbrugge RJ, van Zwam WH, Roozenbeek B, van der Worp HB, Lo RTH, van den\u00a0Wijngaard IR, de Ridder IR, Costalat V, Arquizan C, Lemmens R, Demeestere J,\u00a0Hofmeijer J, Martens JM, Schonewille WJ, Vos JA, Uyttenboogaart M, Bokkers RPH,\u00a0van Tuijl JH, Kortman H, Schreuder FHBM, Boogaarts HD, de Laat KF, van Dijk LC,\u00a0den Hertog HM, van Hasselt BAAM, Brouwers PJAM, Bulut T, Remmers MJM, van Norden\u00a0A, Imani F, Rozeman AD<\/strong>, Elgersma OEH, Desfontaines P, Brisbois D, Samson Y,\u00a0Claren\u00e7on F, Krietemeijer GM, Postma AA, van Doormaal PJ, van den Berg R, van\u00a0der Hoorn A, Beenen LFM, Nieboer D, Lingsma HF, Emmer BJ, Coutinho JM, Majoie\u00a0CBLM, Roos YBWEM; MR CLEAN\u2013NO IV Investigators.<\/p>\n

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Preventive Antibiotics in Stroke Study (PASS): a cost-effectiveness study.<\/em> Prospectief. Multicenter (AMC, ASz en 28 andere Nl ziekenhuizen), juli 2010 – mrt 2014.
Westendorp WF, Zock E<\/strong>, Vermeij J-D, Kerkhoff H<\/strong>, Nederkoorn PJ, Dijkgraaf MGW, van de Beek D, PASS investigators. Neurology May 2018 1; 90(18): e-1553-e1560<\/p>\n<\/div>\n<\/div>\n

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Application of the 2017 revised McDonald criteria for multiple sclerosis to patients with a typical clinically isolated syndrome.\u00a0<\/i>Roos M. van der Vuurst de Vries, MD; Julia Y. Mescheriakova, MD; Yu Yi M. Wong, MD; Tessel F. Runia, MD, PhD; Naghmeh Jafari, MD, PhD;\u00a0 Johnny P. Samijn, MD, PhD; Janet W.K. de Beukelaar<\/b>, MD, PhD; Beatrijs H.A. Wokke, MD, PhD,\u00a0 Theodora A.M. Siepman1, MD; Rogier Q. Hintzen1, MD, PhD.\u00a0Geaccepteerd voor publicatie in : JAMA Neurology, inclusief een Editorial.<\/p>\n

The capability set for work – correlates of sustainable employability in workers with multiple sclerosis.<\/i><\/div>\n
\u00a0van Gorp DAM, van der Klink JJL, Abma FI, Jongen PJ, van Lieshout I, Arnoldus EPJ, Beenakker EAC, Bos HM, van Eijk JJJ, Fermont J, Frequin STFM, de Gans K, Hengstman GJD, Hupperts RMM, Mostert JP, Pop PHM, Verhagen WIM,\u00a0Zemel D<\/b>, Heerings MAP, Reneman MF, Middelkoop HAM, Visser LH, van der Hiele K.<\/div>\n
Health Qual Life Outcomes. 2018 Jun 1;16(1):113. doi: 10.1186\/s12955-018-0942-7.<\/div>\n
\u00a0.<\/div>\n
Coping strategies in relation to negative work events and accommodations in employed multiple sclerosis patients.<\/i><\/div>\n
van der Hiele K, van Gorp D, Benedict R, Jongen PJ, Arnoldus E, Beenakker E, Bos HM, van Eijk J, Fermont J, Frequin S, van Geel BM, Hengstman G, Hoitsma E, Hupperts R, Mostert JP, Pop P, Verhagen W,\u00a0Zemel D<\/b>, Frndak SE, Heerings M, Middelkoop H, Visser LH.<\/div>\n
Mult Scler J Exp Transl Clin. 2016 Nov 24;2:2055217316680638.<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Intrinsic factors influencing help-seeking behaviour in an acute stroke situation.<\/em>
Kwalitatief onderzoek. Monocenter (ASz), sept – nov 2103
E. Zock<\/strong>, MSc, H. Kerkhoff<\/strong>, MD, PhD, R.P. Kleyweg, MD, PhD, D. van de Beek, MD, PhD. Acta Neurologica Belgica 2016; 116, issue 3: 295-301<\/p>\n

Help seeking behavior and onset-to-alarm time in patients with acute stroke: sub- study of the preventive antibiotics in stroke study.<\/em>
Prospectief. Multicenter, substudy van de PASS studie, nov 2012 – mrt 2014
E. Zock<\/strong>, MSc, H. Kerkhoff<\/strong>, MD, PhD, R.P. Kleyweg, MD et al. BMC Neurology 2016, p 1-8<\/p>\n<\/div>\n

The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial.<\/em>
Prospectief. Multicenter (AMC, ASz en 28 andere Nl ziekenhuizen), juli 2010 – mrt 2014
Willeke F Westendorp*, Jan-Dirk Vermeij*, Elles Zock<\/strong> et al. Lancet. 2015; 385: 1519\u20131526.<\/p>\n

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Eerste reactie van pati\u00ebnten na het ontstaan van een beroerte.<\/em>
Retrospectief. Monocenter (ASz), juli – september 2010
E. Zock<\/strong>, MSc, H. Kerkhoff<\/strong>, MD PhD, R.P. Kleyweg, MD, PhD. Nederlands Tijdschrift voor Geneeskunde 2012; 156 (25): A4336<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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PROTOCOL TE STARTEN ONDERZOEK Onderzoeksprotocol PAC-ELR studie (2024) download=“filename” \u00a0 AFGEROND ONDERZOEK Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial. March 2023. The Lancet 401 (10385). DOI: 10.1016\/S0140-6736(23)00575-5. \u00a0 … <\/p>\n

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